- CAS 3397-35-1
- Purity 99%
Good factory supply good Z-LEU-OSU 3397-35-1
- Molecular Formula: C18H22N2O6
- Molecular Weight: 362.382
- Melting Point: 118-120 °C
- Refractive Index: 1.561
- PKA: 10.60±0.46(Predicted)
- PSA： 102.01000
- Density: 1.28 g/cm3
- LogP: 2.26350
Z-LEU-OSU(Cas 3397-35-1) Usage
|
Chemical Description |
Z-Leu-OSu is a chemical used as a reagent for the synthesis of amides. |
InChI:InChI=1/C18H22N2O6/c1-12(2)10-14(17(23)26-20-15(21)8-9-16(20)22)19-18(24)25-11-13-6-4-3-5-7-13/h3-7,12,14H,8-11H2,1-2H3,(H,19,24)
3397-35-1 Relevant articles
Mechanistic implications of the enantioselective addition of alkylzinc reagents to aldehydes catalyzed by nickel complexes with α-amino amide ligands
Escorihuela, Jorge,Burguete, M. Isabel,Ujaque, Gregori,Lledós, Agustí,Luis, Santiago V.
, p. 11125 - 11136 (2016)
The enantioselective alkylation of aldeh...
Efficient access to enantiopure γ4-amino acids with proteinogenic side-chains and structural investigation of γ4- asn and γ4-ser in hybrid peptide helices
Jadhav, Sandip V.,Misra, Rajkumar,Singh, Sumeet K.,Gopi, Hosahudya N.
supporting information, p. 16256 - 16262 (2013/12/04)
Hybrid peptides composed of α- and β-ami...
Bispidine as a secondary structure nucleator in peptides
Haridas,Sadanandan, Sandhya,Sharma, Yogesh K.,Chinthalapalli, Srinivas,Shandilya, Ashutosh
supporting information; experimental part, p. 623 - 626 (2012/03/07)
Here we describe bispidine as a scaffold...
Chiral bis(amino amides) as chiral solvating agents for enantiomeric excess determination of α-hydroxy and arylpropionic acids
Altava, Belen,Burguete, M. Isabel,Carbo, Nolia,Escorihuela, Jorge,Luis, Santiago V.
scheme or table, p. 982 - 989 (2010/08/22)
A family of bis(amino amides) derived fr...
3397-35-1 Process route
-
-
6066-82-6
1-hydroxy-pyrrolidine-2,5-dione
-
-
2018-66-8
Z-Leu-OH
-
-
3397-35-1
Z-L-leucine hydroxysuccinimide ester
Conditions
| Conditions | Yield |
|---|---|
|
With
dmap;
In
dichloromethane;
for 1h;
Ambient temperature;
|
85%
|
|
With
dicyclohexyl-carbodiimide;
|
60%
|
|
|
|
|
With
dicyclohexyl-carbodiimide;
at 0 - 20 ℃;
|
|
|
With
dicyclohexyl-carbodiimide;
In
tetrahydrofuran;
at 0 ℃;
|
|
|
With
dicyclohexyl-carbodiimide;
In
dichloromethane;
|
|
|
With
dicyclohexyl-carbodiimide;
In
N,N-dimethyl-formamide;
at 0 - 20 ℃;
|
|
|
With
dicyclohexyl-carbodiimide;
In
ethyl acetate;
at 20 ℃;
for 20h;
|
|
|
With
dicyclohexyl-carbodiimide;
In
tetrahydrofuran;
at 0 ℃;
for 3h;
|
|
|
With
dicyclohexyl-carbodiimide;
In
tetrahydrofuran;
at 20 ℃;
|
|
|
With
dicyclohexyl-carbodiimide;
In
acetonitrile;
at 0 - 20 ℃;
|
|
|
With
dicyclohexyl-carbodiimide;
In
dichloromethane;
for 0.166667h;
Cooling with ice;
|
|
|
With
dicyclohexyl-carbodiimide;
In
tetrahydrofuran;
at 0 ℃;
for 1h;
|
|
|
With
dicyclohexyl-carbodiimide;
In
tetrahydrofuran;
at 0 - 5 ℃;
for 3h;
Schlenk technique;
|
-
-
3397-35-1
Z-L-leucine hydroxysuccinimide ester
Conditions
| Conditions | Yield |
|---|---|
|
|
|
|
|
122.8 g (84.7%)
|
3397-35-1 Upstream products
-
6066-82-6
1-hydroxy-pyrrolidine-2,5-dione
-
2018-66-8
Z-Leu-OH
3397-35-1 Downstream products
-
40290-56-0
Cbz-Leu-Ser-OMe
-
7801-71-0
N-benzyloxycarbonyl-L-leucyl-L-leucine
-
42537-96-2
N -(N -benzyloxycarbonyl-L-leucyl)-L-isoleucine
-
60668-10-2
[(N-benzyloxycarbonyl-L-leucyl)amino]-methyl-phosphonic acid