- CAS 38948-27-5
- Purity 99%
Location：Home > Others > 4-(2-piperidinoethoxy)aniline
Buy cost-effective 99% pure 4-(2-piperidinoethoxy)aniline 38948-27-5 now
- Molecular Formula: C13H20 N2 O
- Molecular Weight: 220.315
- Vapor Pressure: 6.92E-06mmHg at 25°C
- Melting Point: 67 °C
- Boiling Point: 377.1°Cat760mmHg
- PKA: 8.81±0.10(Predicted)
- Flash Point: 181.9°C
- PSA： 38.49000
- Density: 1.07g/cm3
- LogP: 2.65260
4-(2-piperidinoethoxy)aniline(Cas 38948-27-5) Usage
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General Description |
4-(2-piperidinoethoxy)aniline, also known as N-(2-Piperidinylethoxy)aniline, is a chemical compound with a molecular formula C13H21N3O. It is a white to light brown solid that is commonly used in the synthesis of pharmaceuticals and dyes. 4-(2-piperidinoethoxy)aniline is a versatile building block for the preparation of various biologically active molecules, including antihistamines and anti-cancer agents. It is also used as an intermediate in the production of organic chemicals and can be utilized in the manufacture of veterinary drugs and agrochemicals. Additionally, 4-(2-piperidinoethoxy)aniline can be employed as a corrosion inhibitor and as a component in the formulation of surfactants and lubricants. |
InChI:InChI=1/C13H20N2O/c14-12-4-6-13(7-5-12)16-11-10-15-8-2-1-3-9-15/h4-7H,1-3,8-11,14H2
38948-27-5 Relevant articles
A platinum(ii) phenylphenanthroimidazole with an extended side-chain exhibits slow dissociation from a c-kit G-quadruplex motif
Castor, Katherine J.,Liu, Zhaomin,Fakhoury, Johans,Hancock, Mark A.,Mittermaier, Anthony,Moitessier, Nicolas,Sleiman, Hanadi F.
, p. 17836 - 17845 (2013)
A series of three platinum(II) phenanthr...
Evaluation of 2-(piperidine-1-yl)-ethyl (PIP) as a protecting group for phenols: Stability to ortho-lithiation conditions and boiling concentrated hydrobromic acid, orthogonality with most common protecting group classes, and deprotection via Cope elimination or by mild Lewis acids
Norén, Rolf
, (2021/04/07)
A new protecting group, 2-(piperidine-1-...
MULTI-SUBSTITUTED PYRIMIDINE DERIVATIVES WITH EXCELLENT KINASE INHIBITORY ACTIVITIES
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Page/Page column 0151-0152, (2019/10/29)
Disclosed are a novel pyrimidine derivat...
Design, synthesis, biological evaluation and molecular docking studies of novel 3-aryl-4-anilino-2H-chromen-2-one derivatives targeting ERα as anti-breast cancer agents
Luo, Guoshun,Chen, Mingqi,Lyu, Weiting,Zhao, Ruheng,Xu, Qian,You, Qidong,Xiang, Hua
, p. 2668 - 2673 (2017/05/29)
The estrogen receptor (ER) has played an...
Discovery of biphenyl-based VEGFR-2 inhibitors. Part 3: Design, synthesis and 3D-QSAR studies
Lu, Wen,Li, Pengfei,Shan, Yuanyuan,Su, Ping,Wang, Jinfeng,Shi, Yaling,Zhang, Jie
, p. 1044 - 1054 (2015/03/04)
VEGFR-2 plays an essential role in angio...
38948-27-5 Process route
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866021-30-9
tert-butyl ((4-(2-piperidin-1-yl)ethoxy)phenyl)carbamate
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-
38948-27-5
4-(2-(piperidin-1-yl)ethoxy)aniline
Conditions
| Conditions | Yield |
|---|---|
|
With
trifluoroacetic acid;
In
dichloromethane;
for 0.25h;
|
93%
|
|
With
hydrogenchloride;
In
ethyl acetate;
at 25 ℃;
for 1h;
|
291.7 mg
|
|
In
tetrahydrofuran; dichloromethane;
at 20 ℃;
for 1h;
|
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2008-75-5
N-chloroethylpiperidine hydrochloride
-
-
123-30-8
4-amino-phenol
-
-
38948-27-5
4-(2-(piperidin-1-yl)ethoxy)aniline
Conditions
| Conditions | Yield |
|---|---|
|
With
sodium hydroxide;
In
N,N-dimethyl-formamide;
at 75 ℃;
for 2h;
|
68%
|
38948-27-5 Upstream products
-
92033-76-6
1-[2-(1-piperidinyl)ethoxy]4-nitrobenzene
-
59954-07-3
acetic acid-[4-(2-piperidino-ethoxy)-anilide]
-
85002-97-7
1-(2-(4-nitrophenoxy)ethyl)piperidine hydrochloride
-
866021-30-9
tert-butyl ((4-(2-piperidin-1-yl)ethoxy)phenyl)carbamate
38948-27-5 Downstream products
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38519-98-1
(5,6-dimethyl-benzooxazol-2-yl)-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-amine
-
1430234-73-3
C30 H32 N6 O3
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1567327-14-3
2-(4-(2-(piperidin-1-yl)ethoxy)phenyl)benzo[d][1,2]selenazol-3(2H)-one