- CAS 345-35-7
- Purity 99%
Location：Home > Pharmaceutical > alpha-Chloro-o-fluorotoluene
99% Purity Commercial production alpha-Chloro-o-fluorotoluene 345-35-7 with Cheapest Price
- Molecular Formula: C7H6ClF
- Molecular Weight: 144.576
- Appearance/Colour: Colorless to light yellow liquid
- Vapor Pressure: 1.47mmHg at 25°C
- Melting Point: 36-38 °C
- Refractive Index: n20/D 1.514(lit.)
- Boiling Point: 176.4 °C at 760 mmHg
- Flash Point: 57.2 °C
- PSA： 0.00000
- Density: 1.191 g/cm3
- LogP: 2.56450
alpha-Chloro-o-fluorotoluene(Cas 345-35-7) Usage
InChI:InChI=1/C7H6ClF/c8-5-6-3-1-2-4-7(6)9/h1-4H,5H2
345-35-7 Relevant articles
Synthesis of mono- and difluorobenzyl chlorides by chlorination of mono- and difluorotoluenes with CCl4 and t-BuOCl induced by iron-containing catalysts
Bayguzina, Alfiya R.,Gallyamova, Leysan I.,Khalilov, Leonard M.,Khusnutdinov, Ravil I.
, (2019)
Mono- and difluorobenzyl chlorides were ...
FLUOROINDOLE DERIVATIVES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS
-
Page/Page column 25; 26, (2017/03/28)
The present invention relates to compoun...
Formamides as Lewis Base Catalysts in SNReactions—Efficient Transformation of Alcohols into Chlorides, Amines, and Ethers
Huy, Peter H.,Motsch, Sebastian,Kappler, Sarah M.
supporting information, p. 10145 - 10149 (2016/08/16)
A simple formamide catalyst facilitates ...
2-silyloxy-tetrahydrothienopyridine, salt thereof and process for preparing the same
-
, (2008/06/13)
A 2-silyloxy-4,5,6,7-tetrahydrothieno[3,...
345-35-7 Process route
-
-
95-52-3
2-Fluorotoluene
-
-
345-35-7
2-fluorobenzyl chloride
Conditions
| Conditions | Yield |
|---|---|
|
With
iron(II) chloride tetrahydrate; tert-butylhypochlorite;
at 20 ℃;
for 3h;
Reagent/catalyst;
chemoselective reaction;
Inert atmosphere;
|
36%
|
|
Chlorierung;
|
|
|
With
phosphorus pentachloride;
at 155 ℃;
Einleiten von Chlor; Sonnenlicht;
|
|
|
With
chlorine;
Irradiation;
|
-
-
446-51-5
2-fluorobenzyl alcohol
-
-
345-35-7
2-fluorobenzyl chloride
Conditions
| Conditions | Yield |
|---|---|
|
With
N,N-dimethyl-formamide; 2-Fluorobenzoyl chloride;
In
dichloromethane;
at 20 ℃;
for 12h;
|
80%
|
|
With
phosphorus pentachloride;
In
tetrachloromethane;
at 20 ℃;
for 1h;
|
76%
|
345-35-7 Upstream products
-
95-52-3
2-Fluorotoluene
-
446-51-5
2-fluorobenzyl alcohol
-
65108-14-7
o-fluorobenzyl ion
-
7647-01-0
hydrogenchloride
345-35-7 Downstream products
-
3798-86-5
6-(o-fluorobenzylthio)purine
-
380-69-8
acetylamino-(2-fluoro-benzyl)-malonic acid diethyl ester
-
446-50-4
1-fluoro-2-(iodomethyl)benzene
-
445-25-0
1-(bromo-chloro-methyl)-2-fluoro-benzene