- CAS 43041-12-9
- Purity 99%
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Quality products?make an important contribution to long-term revenue and profitability. Top Quality Chinese Manufacturer supply 43041-12-9 methyl D-prolinate
1.What is the methyl D-prolinate ?
D-Proline Methyl Ester, is a building block used for the synthesis of pharmaceutical compounds, such as Eletriptan (E505000) acting as an Antimigrene.
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67-56-1
methanol
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609-36-9,25191-13-3,37159-97-0,4305-67-3,4607-28-7
rac-Pro-OH
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43041-12-9,52183-82-1,2577-48-2
methyl pyrrolidine-2-carboxylate
Conditions
| Conditions | Yield |
|---|---|
|
With
thionyl chloride;
for 16h;
Reflux;
|
98%
|
|
With
thionyl chloride;
at 0 - 20 ℃;
for 16h;
|
90%
|
|
With
hydrogenchloride;
|
29%
|
|
With
thionyl chloride;
at 40 ℃;
for 2h;
|
|
|
With
hydrogenchloride; potassium carbonate;
|
|
|
With
hydrogenchloride;
at 100 ℃;
for 0.5h;
|
|
|
With
potassium carbonate;
for 0.5h;
|
|
|
With
acetyl chloride;
at 70 ℃;
for 1h;
|
|
|
With
thionyl chloride;
at 20 ℃;
for 24h;
Cooling with ice;
|
|
|
With
hydrogenchloride;
|
|
|
With
thionyl chloride;
|
|
|
With
thionyl chloride;
at 0 ℃;
for 1h;
Reflux;
Inert atmosphere;
|
|
|
With
thionyl chloride;
at 30 ℃;
for 24h;
Cooling with ice;
Inert atmosphere;
|
|
|
With
thionyl chloride;
at 0 - 20 ℃;
|
|
|
With
thionyl chloride;
at 0 - 70 ℃;
for 3.33333h;
|
|
|
With
thionyl chloride;
at 0 ℃;
for 1h;
Inert atmosphere;
Reflux;
|
|
|
With
thionyl chloride;
|
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13515-74-7
N-tritylproline methyl ester
-
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43041-12-9,52183-82-1,2577-48-2
methyl pyrrolidine-2-carboxylate
Conditions
| Conditions | Yield |
|---|---|
|
With
ammonium cerium (IV) nitrate; water; acetic acid;
In
dichloromethane;
at 20 ℃;
for 0.133333h;
Inert atmosphere;
|
96%
|
2.What is the CAS number for methyl D-prolinate ?
The CAS number of methyl D-prolinate is 43041-12-9.
More information of methyl D-prolinate 43041-12-9 are:
|
CAS?Number |
43041-12-9 |
|
Density |
1.055g/cm3 |
|
Boiling Point |
169.9°Cat760mmHg |
|
Flash Point |
56.5°C |
|
Vapor Pressure |
1.51mmHg at 25°C |
|
Refractive Index |
1.447 |
|
HS CODE |
2933990090 |
|
PSA |
38.33000 |
|
LogP |
0.24020 |
|
Pka |
8.23±0.10(Predicted) |
3.What are another words for methyl D-prolinate ?
Synonyms?for?methyl D-prolinate 43041-12-9:(R)-2-(Methoxycarbonyl)pyrrolidine;(R)-Proline methyl ester; (R)-Pyrrolidine-2-carboxylic acid methyl ester;(R)-Pyrrolidine-2-carboxylic acid methyl ester; Methyl(R)-pyrrolidine-2-carboxylate; Methyl D-prolinate
4.What is the molecular formula of methyl D-prolinate?
The chemical formula of ?methyl D-prolinate is?C6H11 N O2 which containing 6 Carbon atoms,11 Hydrogen atoms,1 Nitrogen atoms and 2 Oxygen atoms,and the molecular weight of??methyl D-prolinate?is 129.159.
5.What is methyl D-prolinate (43041-12-9) used for?
Methyl D-prolinate, also known as D-Proline Methyl Ester, is an organic compound that serves as a crucial building block in the synthesis of various pharmaceutical compounds. It is a derivative of the naturally occurring amino acid, proline, with a methyl ester group attached to it. This modification enhances its reactivity and compatibility in chemical reactions, making it a valuable component in the development of new drugs.
InChI:InChI=1/C6H11NO2/c1-9-6(8)5-3-2-4-7-5/h5,7H,2-4H2,1H3/t5-/m1/s1
Relevant articles related to methyl D-prolinate:
|
Article |
Source |
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X-ray Structure-Guided Discovery of a Potent, Orally Bioavailable, Dual Human Indoleamine/Tryptophan 2,3-Dioxygenase (hIDO/hTDO) Inhibitor That Shows Activity in a Mouse Model of Parkinson’s Disease |
Ning, Xiang-Li,Li, Yu-Zhi,Huo, Cui,Deng, Ji,Gao, Cheng,Zhu, Kai-Rong,Wang, Miao,Wu, Yu-Xiang,Yu, Jun-Lin,Ren, Ya-Li,Luo, Zong-Yuan,Li, Gen,Chen, Yang,Wang, Si-Yao,Peng, Cheng,Yang, Ling-Ling,Wang, Zhou-Yu,Wu, Yong,Qian, Shan,Li, Guo-Bo supporting information, p. 8303 - 8332 (2021/06/30) |
|
Design and Synthesis of 56 Shape-Diverse 3D Fragments |
Atobe, Masakazu,Blakemore, David C.,Bond, Paul S.,Chan, Ngai S.,De Fusco, Claudia,Downes, Thomas D.,Firth, James D.,Hubbard, Roderick E.,Jones, S. Paul,Klein, Hanna F.,O'Brien, Peter,Roughley, Stephen D.,Vidler, Lewis R.,Waddelove, Laura,Whatton, Maria Ann,Wheldon, Mary C.,Woolford, Alison J.-A.,Wrigley, Gail L. supporting information, (2020/07/13) |
6.Buy methyl D-prolinate with the best price .
Chengdu Henghui Pharmaceutical Co., Ltd. is a quality supplier of methyl D-prolinate. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on methyl D-prolinate 43041-12-9.