- CAS 71501-46-7
- Purity 99%
Location：Home > Others > 4-(2-chlorophenyl)piperidin-4-ol
China cas 71501-46-7 factory wholesale 4-(2-chlorophenyl)piperidin-4-ol at affordable price
- Molecular Formula: C11H14 Cl N O
- Molecular Weight: 211.691
- Vapor Pressure: 1.42E-05mmHg at 25°C
- Boiling Point: 352.4°C at 760 mmHg
- Flash Point: 166.9°C
- PSA： 32.26000
- Density: 1.216g/cm3
- LogP: 2.23980
4-(2-chlorophenyl)piperidin-4-ol(Cas 71501-46-7) Usage
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General Description |
4-(2-chlorophenyl)piperidin-4-ol, also known as 2-Chloro-4-(4-hydroxy-4-piperidinyl)benzyl alcohol, is a chemical compound with the molecular formula C11H14ClNO. It is a piperidine derivative with a hydroxy group and a chlorophenyl group attached to the piperidine ring. 4-(2-chlorophenyl)piperidin-4-ol has been studied for its potential pharmacological properties, including its role in the development of novel antipsychotic medications. Additionally, it has been investigated for its potential use as a building block in organic synthesis. Overall, 4-(2-chlorophenyl)piperidin-4-ol is a versatile chemical with potential applications in both pharmaceutical and industrial settings. |
InChI:InChI=1/C11H14ClNO/c12-10-4-2-1-3-9(10)11(14)5-7-13-8-6-11/h1-4,13-14H,5-8H2
71501-46-7 Relevant articles
Synthesis and biological evaluation of fluorescent GAT-ligands based on meso-substituted BODIPY dyes
Daerr, Markus,Pabel, J?rg,H?fner, Georg,Mayer, Peter,Wanner, Klaus T.
, p. 301 - 327 (2020)
BODIPY dyes are well known for their out...
Structure-Kinetic Profiling of Haloperidol Analogues at the Human Dopamine D2 Receptor
Fyfe, Tim J.,Kellam, Barrie,Sykes, David A.,Capuano, Ben,Scammells, Peter J.,Lane, J. Robert,Charlton, Steven J.,Mistry, Shailesh N.
, p. 9488 - 9520 (2019/11/11)
Haloperidol is a typical antipsychotic d...
CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREOF
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Paragraph 1415, (2016/02/21)
Disclosed are novel compounds and a meth...
(4-PHENYL-PIPERIDIN-1-YL)-[5-1H-PYRAZOL-4YL)-THIOPHEN-3-YL]-METHANONE COMPOUNDS AND THEIR USE
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Page/Page column 59, (2011/04/19)
The present invention pertains generally...
71501-46-7 Process route
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553630-94-7
4-(2-chlorophenyl)-4-hydroxypiperidine-1-carboxylic acid tert-butyl ester
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71501-46-7
4-(2-chlorophenyl)-4-hydroxypiperidine
Conditions
| Conditions | Yield |
|---|---|
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4-(2-chlorophenyl)-4-hydroxypiperidine-1-carboxylic acid tert-butyl ester;
With
hydrogenchloride;
In
diethyl ether;
at 0 - 20 ℃;
Inert atmosphere;
With
potassium carbonate;
In
dichloromethane; water;
at 20 ℃;
for 1h;
Inert atmosphere;
|
96%
|
|
With
hydrogenchloride;
In
1,4-dioxane;
at 20 ℃;
for 2h;
|
72%
|
|
With
trifluoroacetic acid;
In
dichloromethane;
at 0 ℃;
for 1h;
|
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![tert-butyl 4-(2'-chloro-[1,1'-biphenyl]-2-yl)-4-hydroxypiperidine-1-carboxylate](/upload/2026/8/3dc3c2f1a0d946a4b013c3c5319c7316_45e65ee9-0695-4b93-b62c-0071630515f2.png)
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tert-butyl 4-(2'-chloro-[1,1'-biphenyl]-2-yl)-4-hydroxypiperidine-1-carboxylate
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553630-94-7
4-(2-chlorophenyl)-4-hydroxypiperidine-1-carboxylic acid tert-butyl ester
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71501-46-7
4-(2-chlorophenyl)-4-hydroxypiperidine
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![4-(2'-chloro-[1,1'-biphenyl]-2-yl)piperidin-4-ol](/upload/2026/8/82908ca22e114e38a42a89ae1319def5_84541dec-a87d-48af-ad64-67e3fbe23dde.png)
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553631-16-6
4-(2'-chloro-[1,1'-biphenyl]-2-yl)piperidin-4-ol
Conditions
| Conditions | Yield |
|---|---|
|
With
sulfuric acid;
In
methanol;
for 84h;
|
52%
15% |
71501-46-7 Upstream products
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553630-94-7
4-(2-chlorophenyl)-4-hydroxypiperidine-1-carboxylic acid tert-butyl ester
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79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one
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694-80-4
2-bromo-1-chlorobenzene
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615-41-8
2-iodochlorobenzene